Fourier ptychographic microscope with numerically enhanced resolution and contrast for biomedical imaging applications (acronym: WUTscope-FPM)
Grant Agreement No.: LIDER14/0352/2023
Granting Authority: National Centre for Research and Development (NCBR)
Project duration: 01.04.2024 – 01.04.2027
Project’s Grant Amount: 1 800 000 PLN
Grant Amount for WUT: 1 800 000 PLN
Project Manager at PW: Piotr Zdańkowski, PhD Eng.
Project Team: Maria Cywińska PhD Eng. (PW), Maksymilian Chlipała PhD Eng. (PW), Piotr Arcab (PW), Marzena Stefaniuk PhD Eng. (Nencki PAN), Luiza Stanaszek PhD Eng. (IMDiK PAN)
Partners: Nanecki Institute of Experimental Biology PAS, Institute of Experimental and Clinical Medicine of the Polish Academy of Sciences (IMDiK PAN)
Project description:
The objective of the WUTscope-FPM project is to develop a microscope based on Fourier Ptychographic Microscopy (FPM), a technique enabling high-resolution biomedical imaging across a wide field of view. Utilizing programmable, multi-angle sample illumination, FPM provides exceptional image reconstruction precision, making it highly valuable in biomedical research, including microscopic-level biological analyses.
The project involves developing innovative, neural network-assisted ptychographic reconstruction algorithms, optimizing data acquisition processes, and validating the technology on real biological specimens—both fixed and live. The final outcome of the project will be the development of an FPM demonstrator designed for practical technology demonstration.
