“High-throughput high-resolution quantitative phase microscopy and tomography with spatiotemporal coherence engineering for non-invasive single-cell analysis” (INTENCITY)

“High-throughput high-resolution quantitative phase microscopy and tomography with spatiotemporal coherence engineering for non-invasive single-ce...

Project Manager: Professor Maciej Trusiak

Project Team: Professor Michał Józwik, Piotr Zdańkowski Ph.D., Julianna Winnik Ph.D., Mikołaj Rogalski Ph.D., Juan Martinez-Carranza Ph.D.

Partners: Warsaw University of Technology

Nanjing University of Science and Technology (School of Electronic and Optical Engineering) (China)

Project duration: 01.10.2024 - 30.09.2027

Project’s Grant Amount: 1 870 518,75 PLN

Grant Agreement No.: WPC3/2022/47/INTENCITY/2024

Granting Authority: The National Centre for Research and Development; 3rd Call for Joint Research Projects under Polish-Chinese Cooperation (2022)

Project description:

Cells are the fundamental units defining the structure and functions of living organisms. This project addresses one of the key challenges in cell research: rapid and non-destructive imaging of entire cell populations with subcellular accuracy. The project focuses on developing new fundamental theories, optoelectronic systems, and reconstruction algorithms to enable label-free, high-resolution quantitative phase imaging (2D imaging) with a large field of view and refractive index tomography (3D imaging). These will be based on the engineering of illumination coherence (synthesizing coherent and incoherent light techniques). The goal is to experimentally and numerically drive improvements in the signal-to-noise ratio and overcome classical information throughput limitations of currently available commercial phase microscopy systems.

Link: https://qcilab.mchtr.pw.edu.pl/

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